Repository of Research and Investigative Information

Repository of Research and Investigative Information

Kurdistan University of Medical Sciences

Predictors of treatment retention in a major methadone maintenance treatment program in Iran: A survival analysis

(2014) Predictors of treatment retention in a major methadone maintenance treatment program in Iran: A survival analysis. Journal of Research in Health Sciences.

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background: To study correlates which are related to retention time of a cohort study of the opioid-dependent patients participating in the Methadone Maintenance Treatment (MMT) program offered by a major addiction treatment clinic in Tehran, Iran between April 2007 and March 2011. Methods: Several parametric Survival models assuming Weibull, Log-normal and Log-logistic distributions were compared to search for association between covariates and risk of relapse and dropping out of treatment among 198 patient participants. Results: According to Akaike Information Criterion (AIC), Log-normal model had the best fitting. Estimates of this model indicated that increase in average methadone dosage was associated with longer retention time. Correlates associated with shorter retention time were suffering from mental disorders, using stimulant drugs, being poly-substance dependents and having prior treatments. Conclusions: Findings of this study provide support for giving more attention to patients who are poly-substance or stimulant-drug dependents, have non-substance psychiatric comorbidity and the ones with addiction treatment history. Independent of patient characteristics, retention improved as the dose of methadone increased. © 2014, Health Hamadan University of Medical Sciences. All rights reserved.

Item Type: Article
Keywords: central stimulant agent; methadone; methadone; narcotic analgesic agent, adolescent; Article; cohort analysis; controlled study; drug dose increase; female; health program; human; Iran; major clinical study; male; mental disease; methadone treatment; opiate addiction; outcome assessment; patient compliance; practice guideline; prediction; recurrence risk; relapse; retrospective study; statistical model; statistical parameters; survival; treatment response; adult; opiate substitution treatment; Opioid-Related Disorders; patient attitude; procedures; regression analysis; statistics and numerical data; young adult, Adult; Analgesics, Opioid; Female; Humans; Iran; Male; Methadone; Opiate Substitution Treatment; Opioid-Related Disorders; Patient Acceptance of Health Care; Regression Analysis; Retrospective Studies; Survival Analysis; Young Adult
Page Range: pp. 291-295
Journal or Publication Title: Journal of Research in Health Sciences
Volume: 14
Number: 4
Publisher: Health Hamadan University of Medical Sciences
ISSN: 16822765
Depositing User: مهندس جمال محمودپور
URI: http://eprints.muk.ac.ir/id/eprint/1084

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