(2019) The effects of omega-3 and branched-chain amino acids supplementation on serum apoptosis markers following acute resistance exercise in old men. Journal of Aging and Physical Activity.
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Abstract
The potential benefits of omega-3 fatty acids and branched-chain amino acids (BCAAs) supplements on exercise-induced apoptosis are not clear. In a crossover randomized study, 11 men (age = 62.8 ± 2.2 years) performed an acute bout of resistance exercise and underwent 1-week supplementation with either 20 g of BCAA or 2,700 mg of omega-3/day. Subjects performed the same exercise after supplementation protocols. Following a 3-week washout period, subjects switched groups. Circulating levels of soluble Fas ligand (sFasL), cytochrome c, Bax, Bcl-2, and nuclear factor-kappa B were measured before and immediately after exercise sessions. sFasL, cytochrome c, and Bax increased after exercise. Simple main effect of time on sFasl was significant in control trial but not in omega-3 and BCAA trials. There were no differences in nuclear factor-kappa B and Bcl-2 between control and supplement trials. This study showed that adding omega-3 fatty acids or BCAA to the dietary regime of old men could partially attenuate resistance exercise-induced apoptosis. © 2019 Human Kinetics, Inc.
Item Type: | Article |
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Keywords: | cell death; docosahexaenoic acid; eicosapentaenoic acid; strength |
Page Range: | pp. 198-204 |
Journal or Publication Title: | Journal of Aging and Physical Activity |
Volume: | 27 |
Number: | 2 |
Publisher: | Human Kinetics Publishers Inc. |
Identification Number: | 10.1123/japa.2017-0404 |
ISSN: | 10638652 |
Depositing User: | مهندس جمال محمودپور |
URI: | http://eprints.muk.ac.ir/id/eprint/1808 |
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