Repository of Research and Investigative Information

Repository of Research and Investigative Information

Kurdistan University of Medical Sciences

The effects of omega-3 and branched-chain amino acids supplementation on serum apoptosis markers following acute resistance exercise in old men

(2019) The effects of omega-3 and branched-chain amino acids supplementation on serum apoptosis markers following acute resistance exercise in old men. Journal of Aging and Physical Activity.

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

The potential benefits of omega-3 fatty acids and branched-chain amino acids (BCAAs) supplements on exercise-induced apoptosis are not clear. In a crossover randomized study, 11 men (age = 62.8 ± 2.2 years) performed an acute bout of resistance exercise and underwent 1-week supplementation with either 20 g of BCAA or 2,700 mg of omega-3/day. Subjects performed the same exercise after supplementation protocols. Following a 3-week washout period, subjects switched groups. Circulating levels of soluble Fas ligand (sFasL), cytochrome c, Bax, Bcl-2, and nuclear factor-kappa B were measured before and immediately after exercise sessions. sFasL, cytochrome c, and Bax increased after exercise. Simple main effect of time on sFasl was significant in control trial but not in omega-3 and BCAA trials. There were no differences in nuclear factor-kappa B and Bcl-2 between control and supplement trials. This study showed that adding omega-3 fatty acids or BCAA to the dietary regime of old men could partially attenuate resistance exercise-induced apoptosis. © 2019 Human Kinetics, Inc.

Item Type: Article
Keywords: cell death; docosahexaenoic acid; eicosapentaenoic acid; strength
Page Range: pp. 198-204
Journal or Publication Title: Journal of Aging and Physical Activity
Volume: 27
Number: 2
Publisher: Human Kinetics Publishers Inc.
Identification Number: 10.1123/japa.2017-0404
ISSN: 10638652
Depositing User: مهندس جمال محمودپور
URI: http://eprints.muk.ac.ir/id/eprint/1808

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