Repository of Research and Investigative Information

Repository of Research and Investigative Information

Kurdistan University of Medical Sciences

In vitro activity of nine antifungal agents against a global collection of Hortaea werneckii isolates, the agent of tinea nigra

(2019) In vitro activity of nine antifungal agents against a global collection of Hortaea werneckii isolates, the agent of tinea nigra. International Journal of Antimicrobial Agents.

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Abstract

The in vitro susceptibility of molecularly identified Hortaea werneckii isolates (n = 37), the causative agent of tinea nigra, originating from clinical and environmental sources was determined for nine antifungal agents. Posaconazole had the lowest geometric mean minimum inhibitory concentration (GM MIC)(0.07 µg/mL), followed by voriconazole (0.13 µg/mL), isavuconazole (0.14 µg/mL), itraconazole (0.16 µg/mL), terbinafine (0.19 µg/mL)and amphotericin B (0.92 µg/mL). In contrast, fluconazole (14.56 µg/mL), caspofungin (2.41 µg/mL)and anidulafungin (1.42 µg/mL)demonstrated the highest GM MICs/MECs against H. werneckii. © 2019 Elsevier Ltd

Item Type: Article
Keywords: Hortaea werneckii; In vitro susceptibility; Isavuconazole; Tinea nigra
Journal or Publication Title: International Journal of Antimicrobial Agents
Identification Number: 10.1016/j.ijantimicag.2019.05.006
Depositing User: مهندس جمال محمودپور
URI: http://eprints.muk.ac.ir/id/eprint/1818

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