Repository of Research and Investigative Information

Repository of Research and Investigative Information

Kurdistan University of Medical Sciences

The Effect of Pregabalin on the Prevention of Succinylcholine-Induced Fasciculation and Myalgia

(2020) The Effect of Pregabalin on the Prevention of Succinylcholine-Induced Fasciculation and Myalgia. Journal of Perianesthesia Nursing.

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Abstract

Purpose: This study evaluates the effect of pregabalin on fasciculation and myalgia after using succinylcholine. Design: This randomized double-blind prospective study was conducted among 100 patients aged 20 to 60 years old. Methods: Pregabalin (300 mg) and placebo (in capsule form) were placed in similar containers. The results were analyzed by SPSS 23 software, and statistical analysis consisted of χ2 test and t test, and a P value less than .05 was considered significant. Findings: The mean pain score in the group receiving pregabalin was lower than the placebo group. According to the χ2 test, there was a significant difference between the two groups in the frequency of fasciculation (P = .003). Mean fasciculation severity in the pregabalin group was lower than placebo group. According to t test, there was a significant difference in the mean fasciculation severity between the two groups (P = .002). Conclusions: This study showed that 300 mg of pregabalin was effective in reducing postoperative fasciculation and myalgia in patients treated with succinylcholine. © 2019 American Society of PeriAnesthesia Nurses

Item Type: Article
Keywords: fasciculation; myalgia; pregabalin; succinylcholine
Page Range: pp. 255-259
Journal or Publication Title: Journal of Perianesthesia Nursing
Volume: 35
Number: 3
Identification Number: 10.1016/j.jopan.2019.11.005
Depositing User: مهندس جمال محمودپور
URI: http://eprints.muk.ac.ir/id/eprint/2304

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