Repository of Research and Investigative Information

Repository of Research and Investigative Information

Kurdistan University of Medical Sciences

Does Helicobacter pylori infection play a role in susceptibility to brucellosis?

(2017) Does Helicobacter pylori infection play a role in susceptibility to brucellosis? Japanese Journal of Infectious Diseases.

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Brucellosis is endemic in Iran. Several studies have shown that brucellosis is associated with other infectious diseases. This study aimed to determine the relationship between Helicobacter pylori (HP) and brucellosis. In this case-control study, 100 patients with brucellosis as cases and 200 participants without brucellosis as controls were evaluated. To compare the prevalence of HP in the 2 groups, odds ratios and confidence intervals for every variable were analyzed using logistic regression models after adjustment for confounding factors. The results obtained in patients with brucellosis showed that fever, sweating, and joint pain were the most prevalent clinical symptoms. In addition, compared with the control group, there was a significant relationship between the IgM antibody to HP and brucellosis infection (estimated odds ratio 2.74; 95 CI: 1.5–4.9) (p = 0.001). Acute infection with HP was associated with brucellosis and increased the risk of brucellosis infection. © 2017, National Institute of Health. All rights reserved.

Item Type: Article
Keywords: immunoglobulin G; immunoglobulin M antibody, adult; antibiotic sensitivity; arthralgia; Article; brucellosis; controlled study; Coombs test; cross-sectional study; disease association; endemic disease; enzyme linked immunosorbent assay; female; fever; Helicobacter infection; Helicobacter pylori; human; Iran; major clinical study; male; observational study; prevalence; rural area; sweating; urban area
Page Range: pp. 672-674
Journal or Publication Title: Japanese Journal of Infectious Diseases
Volume: 70
Number: 6
Publisher: National Institute of Health
Identification Number: 10.7883/yoken.JJID.2017.043
ISSN: 13446304
Depositing User: مهندس مهدی شریفی

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