Repository of Research and Investigative Information

Repository of Research and Investigative Information

Kurdistan University of Medical Sciences

Biomonitoring of tobacco smoke exposure and self-reported smoking status among general population of Tehran, Iran

(2016) Biomonitoring of tobacco smoke exposure and self-reported smoking status among general population of Tehran, Iran. Environmental Science and Pollution Research.

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The present study aimed to find a correlation between the self-reported smoking status of the residents of Tehran, Iran, and the urine cotinine as a biomarker of exposure to tobacco smoke. The self-reported data was collected from 222 participants who were living in the urban area of Tehran. The urine samples of participants were collected for cotinine analysis. Urine cotinine was measured by an enzymatic immunoassay technique. Tobacco smoking was reported by 76 (34.23 ) participants as the self-reported data, and the number of males in this report was higher than of females (p < 0.001). By adding the number of the self-reported non-smokers with cotinine levels above the cutoff value of >100 ng/ml to self-reported smokers, the smoking prevalence increased from 34.23 (95 CI 28.01–40.88 ) to 36.48 (95 CI 30.14–43.19 ). Using the cutoff value, sensitivity and specificity of the self-reported smoking status were respectively 90.12 (95 CI 81.46–95.64 ) and 98 (95 CI 93.91–99.55 ). The levels of agreement between self-reported tobacco smoking and urinary cotinine concentrations was 95.1 (k = 0.89, p < 0.001, 95 CI = 0.81–0.95). Based on the results, self-reported smoking can be a valid marker for assessing the tobacco exposure, and it can be of use in large epidemiological studies. © 2016, Springer-Verlag Berlin Heidelberg.

Item Type: Article
Keywords: alkaloid; biomarker; biomonitoring; concentration (composition); disease prevalence; enzyme activity; immunoassay; pollution exposure; smoking; tobacco; urban area; urine, Iran; Tehran Iran, Nicotiana tabacum, biological marker; cotinine; passive smoking; smoke, adult; analysis; environmental monitoring; enzyme immunoassay; epidemiology; female; human; Iran; male; middle aged; passive smoking; prevalence; procedures; self report; smoke; smoking; tobacco; urine; young adult, Adult; Biomarkers; Cotinine; Environmental Monitoring; Female; Humans; Immunoenzyme Techniques; Iran; Male; Middle Aged; Prevalence; Self Report; Smoke; Smoking; Tobacco; Tobacco Smoke Pollution; Young Adult
Page Range: pp. 25065-25073
Journal or Publication Title: Environmental Science and Pollution Research
Volume: 23
Number: 24
Identification Number: 10.1007/s11356-016-7619-8
Depositing User: مهندس جمال محمودپور

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