Abstract

This double-blind clinical trial was conducted on 60 patients with hair loss referring to the clinic or private office in 2015 to investigate the therapeutic effects of Minoxidil 1 shampoo on hair loss in people with alopecia. Patients who had inclusion criteria were randomly divided in two intervention and control groups. In the intervention group minoxidil 1 shampoo was used on every other day for 4 months. In the control group, placebo-shampoo (quite "similar to the shampoo which was used in intervention group) was given. The average number of vellus hair before intervention was 10.4 ± 10.1that after three months of the intervention was increased to 12.3 ± 9.1, also it was increased in the control group from 8.5 ± 6.5 to 9.6 ± 5.8, but there was no significant differences between two groups (p=0.19). Also the number of terminal hair in the intervention group before using Minoxidil 1 shampoo was 24.2 ± 21.0 that after the four months of intervention reached to 26.9 ± 21.9, it was increased in the control group from 22.9 ± 16.1 to 23.1 ± 16.1,but there was no significant differences between two groups (p=0.27).Although Minoxidil shampoo has positive effects in improving patients, but to draw conclusions about the efficacy of Minoxidil shampoo three months is a short time and long-term studies are necessary.