Repository of Research and Investigative Information

Repository of Research and Investigative Information

Kurdistan University of Medical Sciences

Production of SARS-CoV-2 Antibodies and Emergence of the Clinical Symptoms of COVID-19

(2021) Production of SARS-CoV-2 Antibodies and Emergence of the Clinical Symptoms of COVID-19. Iranian journal of allergy, asthma, and immunology.

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Abstract

Coronavirus disease 2019 (COVID-19) is a worldwide public health problem that has attracted much attention due to its clinical findings. Measurement of IgG and IgM antibodies is of great importance for researchers and it will help to develop a new diagnostic and therapeutic method in clinical care. In this cross-sectional study, we aim to measure the IgG and IgM antibody levels in 401 suspected COVID-19 volunteers. We also measure the time duration for the appearance of IgG and IgM antibodies from the onset of symptoms to sampling time. Of 401 participants enrolled in the study, 255 (63.59) were healthy, 79 (19.70) were a carrier, 59 (14.71) were cured and 8 (1.99) were borderline. Of 142 subjects diagnosed with COVID-19, 41 (28.87) presented with gastrointestinal (GI) symptoms, 83 (58.45) had no GI symptoms, and 18 (12.68) were asymptomatic. According to our findings, the measurement of IgG and IgM antibodies will provide the tool for the diagnosis of COVID-19 and significantly boost research into novel diagnostic and therapeutic approaches.

Item Type: Article
Keywords: immunoglobulin G; immunoglobulin M; virus antibody, adult; aged; blood; clinical trial; cross-sectional study; diagnosis; female; human; male; metabolism; middle aged, Adult; Aged; Antibodies, Viral; COVID-19; COVID-19 Serological Testing; Cross-Sectional Studies; Female; Humans; Immunoglobulin G; Immunoglobulin M; Male; Middle Aged; SARS-CoV-2
Subjects: WC Communicable Diseases > WC 500-590 Virus Diseases
Divisions: Research Vice-Chancellor Department > Social Determinants of Health Research Center
Page Range: pp. 244-248
Journal or Publication Title: Iranian journal of allergy, asthma, and immunology
Journal Index: Pubmed
Volume: 20
Number: 2
Publisher: NLM (Medline)
ISSN: 17355249
Depositing User: مسعود رسول آبادی
URI: http://eprints.muk.ac.ir/id/eprint/5148

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