Repository of Research and Investigative Information

Repository of Research and Investigative Information

Kurdistan University of Medical Sciences

Functional survey of decellularized tissues transplantation for infertile females

(2022) Functional survey of decellularized tissues transplantation for infertile females. Cell and tissue banking.

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/34806123

Abstract

Numbers of women worldwide face infertility, which will have a significant impact on a couple's life. As a result, assisting with the treatment of these individuals is seen as a critical step. Successful births following uterus and ovary donation have been reported in recent. When immunosuppressive drugs are used in patients who receive donated tissues, there are always problems with the drugs' side effects. In recent years, tissue engineering has mainly been successful in treating infertility using decellularization techniques. Engineered uterus and ovary prevent immunological reactions and do not require immunosuppressive drugs. The most important aspect of using decellularized tissue is its proper function after transplantation. These tissues must be able to produce follicles, secrete hormones and cause pregnancy. This study aimed to investigate research on decellularized tissues and transplanted into the female reproductive system. In this study, just tissues that, after transplantation, have the proper function for fertility were investigated.

Item Type: Article
Keywords: Female Fertility Humans *Infertility/therapy *Ovary/transplantation Pregnancy Tissue Engineering/methods Tissue Scaffolds Uterus/transplantation Decellularized tissue Infertility Reproductive system Tissue engineering
Page Range: pp. 407-415
Journal or Publication Title: Cell and tissue banking
Volume: 23
Number: 3
Depositing User: مهندس مهدی شریفی
URI: http://eprints.muk.ac.ir/id/eprint/5311

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