Repository of Research and Investigative Information

Repository of Research and Investigative Information

Kurdistan University of Medical Sciences

Estimation of incidence and evaluation of clinical and paraclinical features of cystic fibrosis: A rare disease in Kurdistan province during 2010-2020

(2023) Estimation of incidence and evaluation of clinical and paraclinical features of cystic fibrosis: A rare disease in Kurdistan province during 2010-2020. Scientific Journal of Kurdistan University of Medical Sciences.

Full text not available from this repository.

Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background and Aim: Cystic fibrosis as a rare genetic disease that causes widespread inflammation in the body and is diagnosed with a poor prognosis due to various complications, especially respiratory system involvement. The aim of this study was to estimate the incidence of cystic fibrosis and determine its epidemiological, clini,cal and paraclinical features in Kurdistan province, Iran, between 2010-2020. Materials and Methods: This cross-sectional study was performed on cystic fibrosis patients who were admitted to Besat Hospital in Sanandaj (as the only referral specialized center for pediatric diseases in Kurdistan province) from 2010-to 2011. Epidemiological, clini,cal and paraclinical data of patients were collected using a checklist and analyzed in SPSS software version 22 using the Mann-Whitney test and Spearman correlation coefficient. Results: During the years under study, 19 patients were definitively diagnosed with cystic fibrosis, of which 14 (73.7) were male. The mean and standard deviation of their age was 11.10 ± 9.7. Based on the data of the province's births in the period under review, the incidence of cystic fibrosis in Kurdistan province is estimated at about one in every 15,000 live births per year. In 4 patients (21.1), there was a positive family history. The main symptoms of these patients were steatorrhea (94.7), cough (89.5), dyspnea (78.9), growth disorder (73.7), heart disorders (63.2), jaundice (57.9) and finger clubbing (36.8). Conclusion: Although cystic fibrosis is not very common in this province but identifying at-risk parents and early identification of these patients can be helpful in increasing life expectancy and quality of life and reducing health costs. © 2018 the Author (s).

Item Type: Article
Keywords: Cystic fibrosis Genetic disorder Incidence Kurdistan Article checklist child clinical article clinical evaluation correlation coefficient cross-sectional study family history female human Iran life expectancy male quality of life rare disease
Page Range: pp. 54-67
Journal or Publication Title: Scientific Journal of Kurdistan University of Medical Sciences
Volume: 27
Number: 6
Depositing User: مهندس مهدی شریفی
URI: http://eprints.muk.ac.ir/id/eprint/5746

Actions (login required)

View Item View Item