Repository of Research and Investigative Information

Repository of Research and Investigative Information

Kurdistan University of Medical Sciences

Role of diffusion tensor imaging as an imaging biomarker and theranostic tool in structural imaging of traumatic brain injury

(2016) Role of diffusion tensor imaging as an imaging biomarker and theranostic tool in structural imaging of traumatic brain injury. Journal of Chemical and Pharmaceutical Sciences.

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Neuroimaging technology is at a "newborn" stage in the evaluation of TBI. While additional literature are obviously required to decide whether these modalities and progress in knowledge with noninvasive monitors will allow early and consistent recognition of revocable secondary brain damages, the final query is whether these new modalities will help in treatment plans that will absolutely mark result. DTI is an influential instrument for assessing white matter anatomy and related anomalies. DTI was formerly an investigation tool, but is using clinical practice. Accepting the terms and basic ideas of this method can aid in the clinical implementation and interpretation of this blend of structural and physiologic white matter evaluation. In conclusion, although DTI is as a diagnostic tool for severity of TBI and as an outcome predictor, but severe preclinical and clinical validation of each imaging method should be a top importance.

Item Type: Article
Keywords: biological marker, Article; brain blood flow; computed tomographic angiography; computer assisted tomography; corpus callosum; diffuse axonal injury; diffusion tensor imaging; fractional anisotropy; human; hypoxic ischemic encephalopathy; injury severity; neuroanatomy; neuroimaging; nuclear magnetic resonance imaging; nuclear magnetic resonance spectroscopy; occipital lobe; pathophysiology; perfusion weighted imaging; spectroscopy; spin labeling; theranostic nanomedicine; traumatic brain injury; white matter
Page Range: pp. 854-864
Journal or Publication Title: Journal of Chemical and Pharmaceutical Sciences
Volume: 9
Number: 2
Publisher: SPB Pharma Society
ISSN: 09742115
Depositing User: مهندس جمال محمودپور
URI: http://eprints.muk.ac.ir/id/eprint/589

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