Repository of Research and Investigative Information

Repository of Research and Investigative Information

Kurdistan University of Medical Sciences

Predictors of tuberculosis in hiv/aids patients referred to behavioral diseases consultation center: A registry-based study in Abadan, Southwest of Iran

(2016) Predictors of tuberculosis in hiv/aids patients referred to behavioral diseases consultation center: A registry-based study in Abadan, Southwest of Iran. Shiraz E Medical Journal.

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background: In the world, it is estimated that 36.9 million people are living with HIV (PLHIV). Tuberculosis (TB) remains as the leading cause of death among PLHIV. This study aimed to determine the predictors of TB among HIV positive patients. Methods: This cross-sectional study was based on the data from 366 patients with HIV/AIDS acquired from 2010 to 2013 in Abadan andKhorramshahrcities, southwest of Iran. Demographicandclinical datawereobtainedfrompatients’ medical records inAbadan and Khorramshahr triangular clinics. Univariate and multivariable binary logistic regression models were used to identify TB predictors among HIV/AIDS patients. Results: The prevalence of TB patients was 21.9 among HIV patients. About 57.4 of the patients were below 35 years of age, and most of them (85.5) were male. Univariate logistic regression showed a statistically significant association between the occurrence of TB and explanatory variables including sex, imprisonment history, HCV and HBV status, addiction, stage of disease, CD4 cell and TLC (Total lymphocyte count) count. In multivariate analysis, being addicted (adjusted OR = 7.03, 95 CI: 1.28, 38.66) and positive HBV (adjusted OR = 4.28, 95 CI: 1.53, 12.00) were associated with incidence of TB after adjusting for age, sex, phase at diagnosis, addiction and HBV status. Conclusions: Addiction and HBV infection can be considered as predictors of incidence of TB in HIV/AIDS patients then early diagnosis of TB especially in higher-risk groups, such as those with addiction and HBV infection is recommended. © 2016, Shiraz University of Medical Sciences.

Item Type: Article
Keywords: acquired immune deficiency syndrome; addiction; adolescent; adult; Article; CD4 lymphocyte count; child; comorbidity; cross-sectional study; female; hepatitis B; Hepatitis B virus; Hepatitis C virus; human; Human immunodeficiency virus infection; incidence; infant; major clinical study; male; mixed infection; predictor variable; prevalence; risk factor; sex difference; tuberculosis
Journal or Publication Title: Shiraz E Medical Journal
Volume: 17
Number: 10
Publisher: Shiraz University of Medical Sciences
Identification Number: 10.17795/semj41542
ISSN: 17351391
Depositing User: مهندس جمال محمودپور
URI: http://eprints.muk.ac.ir/id/eprint/702

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