Repository of Research and Investigative Information

Repository of Research and Investigative Information

Kurdistan University of Medical Sciences

Randomized comparative clinical trial of Artemisia sieberi 5 lotion and clotrimazole 1 lotion for the treatment of pityriasis versicolor

(2008) Randomized comparative clinical trial of Artemisia sieberi 5 lotion and clotrimazole 1 lotion for the treatment of pityriasis versicolor. Indian Journal of Dermatology.

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Aims: To compare the therapeutic effects of topical Artremisia sieberi 5 lotion with topical clotrimazole 1 lotion in the treatment of pityriasis versicolor. Materials and Methods: 100 patients with pityriasis versicolor and microscopic identification of Malassezia furfur were randomly assigned to treatment with either topical Artemisia sieberi 5 lotion (group 1) or topical clotrimazole 1 lotion (group 2) for 2 weeks. Group 1 and group 2 consisted of 51 and 49 patients respectively. The patients were evaluated both clinically and mycologically at baseline and every 2 weeks for a period of 4 weeks. Results: At the end of the second week, clinical cure rates were 86.3 and 65.3 for group 1 and group 2 respectively ( P < 0.01), but at the same time mycological cure rate was 92.2 for group 1 and 73.5 for group 2 ( P < 0.05). At the end of the fourth week, clinical cure rates were 86.3 and 59.2 for group 1 and group 2 respectively ( P < 0.01), and at the same time mycologic cure rate was 96.1 for group 1 and 65.3 for group 2 ( P < 0.01). Conclusions: The results of this study demonstrated that Artemisia sieberi 5 lotion was more effective than clotrimazole 1 lotion in the treatment of pityriasis versicolor.

Item Type: Article
Keywords: Artemisia sieberi extract; clotrimazole; plant extract; unclassified drug, add on therapy; adolescent; adult; Artemisia; article; clinical trial; controlled clinical trial; controlled study; double blind procedure; drug effect; female; human; major clinical study; Malassezia furfur; male; mycology; randomized controlled trial; skin defect; tinea versicolor
Page Range: pp. 115-118
Journal or Publication Title: Indian Journal of Dermatology
Volume: 53
Number: 3
Publisher: Medknow Publications and Media Pvt. Ltd
Identification Number: 10.4103/0019-5154.43209
ISSN: 00195154
Depositing User: مهندس جمال محمودپور
URI: http://eprints.muk.ac.ir/id/eprint/1613

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