Repository of Research and Investigative Information

Repository of Research and Investigative Information

Kurdistan University of Medical Sciences

Comparison between the four-field box and field-in-field techniques for conformal radiotherapy of the esophagus using dose–volume histograms and normal tissue complication probabilities

(2017) Comparison between the four-field box and field-in-field techniques for conformal radiotherapy of the esophagus using dose–volume histograms and normal tissue complication probabilities. Japanese Journal of Radiology.

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Purpose: We evaluated and compared the performance of the field-in-field (FIF) to that of the four-field box (4FB) technique regarding dosimetric and radiobiological parameters for radiotherapy of esophageal carcinoma. Materials and methods: Twenty patients with esophageal cancer were selected. For each patient, two treatment plans were created: 4FB and FIF. The parameters compared included the conformity index (CI), homogeneity index (HI), Dmean, Dmax, tumor control probability (TCP), V20Gy and V30Gy of the heart and lungs, normal tissue complication probability (NTCP), and monitor units per fraction (MU/fr). Results: A paired t-test analysis did not show any significant differences (p > 0.05) between the two techniques in terms of the CI and TCP. However, the HI significantly improved when the FIF was applied. Dmax of the PTV, lung, and spinal cord were also significantly better with the FIF. Moreover, the lung V20Gy as well as the NTCPs of the lung and spinal cord significantly reduced when the FIF was used, and the MU/fr was significantly decreased. Conclusions: The FIF showed evident advantages over 4FB: a more homogeneous dose distribution, lower Dmax values, and fewer required MUs, while it also retained PTV dose conformality. FIF should be considered as a simple technique to use clinically in cases with esophageal malignancies, especially in clinics with no IMRT. © 2017, Japan Radiological Society.

Item Type: Article
Keywords: adult; Article; cancer radiotherapy; clinical article; conformal radiotherapy; conformity index; dosimetry; esophagus carcinoma; field in field technique; four field box technique; heart tissue; homogeneity index; human; intermethod comparison; linear accelerator; liver disease; liver tissue; lung parenchyma; male; monitor unit per fraction; multileaf collimator; myelitis; normal tissue complication probability; organs at risk; pericarditis; priority journal; radiation dose distribution; radiation injury; radiation pneumonia; radiobiology; radiological parameters; radiotherapy planning system; radiotherapy unit; spinal cord; treatment planning; tumor control probability
Page Range: pp. 327-334
Journal or Publication Title: Japanese Journal of Radiology
Volume: 35
Number: 6
Publisher: Springer Tokyo
Identification Number: 10.1007/s11604-017-0637-8
ISSN: 18671071
Depositing User: مهندس مهدی شریفی
URI: http://eprints.muk.ac.ir/id/eprint/230

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